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With the extra volume of blood hitting stiffer arteries during exercise, large increases in systolic hypertension have caused worry until this could damage the guts. The usage of both toprol and metoprolol could cause some lopressor side effects like diareahea, constipation, insomnia, nausea, depression, memory loss, fever, low blood pressure and could possibly be impotence. People who've been identified as having diabetes need being cautious about blood pressure, for their disease can harm their kidneys. Patients must also avoid having a drink given it may worsen the negative effects of taking metoprolol. This medication can benefit several mood disorders.